Announcement date
2019/08/31
Responsible:
Rebekah L. Gundry . Medical College of Wisconsin, USA
Description
To generate glycan structure libraries, the current study used porous graphitized carbon (PGC) LC interfaced with MS (PGC-LC-MS), a technique that resolves glycan structures and enables characterization and quantification of individual structures. By applying this approach to primary human heart tissue homogenate, cardiomyocytes (CM) enriched from human heart tissue, and human induced pluripotent stem cell derived CM (hiPSC-CM), this study establishes reference structure libraries of the cardiac glycome containing 265 N- and O-glycans.
Sample preparation
N/A
Liquid chromatography
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MS
1. General features
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2. Ion sources
N/A
3. Ion transfer optics
N/A
