Structure

    redEnd--??1D-Man,p--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p)--??1S$MONO,Und,-H,0,redEnd

The O-glycome of human nigrostriatal tissue and its alteration in Parkinsons disease

GlyTouCan Accession Number: Loading...

Peak Intensity
222.84 0.8
225.01 0.8
240.95 1.5
243.08 1.1
259.17 0.7
261.27 2.2
264.26 1.5
266.14 1.1
284.22 0.7
300.99 0.6
315.15 6.3
317.06 0.6
333.24 0.7
343.09 0.6
361.0 0.7
363.24 0.6
401.17 1.1
403.25 0.8
407.04 1.3
407.43 0.6
408.44 1.0
426.12 1.4

Annotations:

BZ ?1D-Man,p/#bcleavage--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p/#zcleavage)--??1S$MONO,Und,-H,0,redEnd
427.31 0.7
428.28 14.5

Annotations:

BY ?1D-Man,p/#bcleavage--??1D-GlcNAc,p((--??1D-Gal,p/#ycleavage)--??1L-Fuc,p)--??1S$MONO,Und,-H,0,redEnd CZ ?1D-Man,p/#ccleavage--??1D-GlcNAc,p((--??1D-Gal,p/#zcleavage)--??1L-Fuc,p)--??1S$MONO,Und,-H,0,redEnd ZZ redEnd--??1D-Man,p--??1D-GlcNAc,p((--??1D-Gal,p/#zcleavage)--??1L-Fuc,p/#zcleavage)--??1S$MONO,Und,-H,0,redEnd
429.13 3.6
431.2 1.3
444.15 9.1

Annotations:

BY ?1D-Man,p/#bcleavage--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p/#ycleavage)--??1S$MONO,Und,-H,0,redEnd CZ ?1D-Man,p/#ccleavage--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p/#zcleavage)--??1S$MONO,Und,-H,0,redEnd
444.49 2.8

Annotations:

BY ?1D-Man,p/#bcleavage--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p/#ycleavage)--??1S$MONO,Und,-H,0,redEnd CZ ?1D-Man,p/#ccleavage--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p/#zcleavage)--??1S$MONO,Und,-H,0,redEnd
444.95 2.3
445.26 0.9
445.56 0.8
446.21 2.3

Annotations:

CY ?1D-Man,p/#ccleavage--??1D-GlcNAc,p((--??1D-Gal,p/#ycleavage)--??1L-Fuc,p)--??1S$MONO,Und,-H,0,redEnd YZ redEnd--??1D-Man,p--??1D-GlcNAc,p((--??1D-Gal,p/#ycleavage)--??1L-Fuc,p/#zcleavage)--??1S$MONO,Und,-H,0,redEnd ZY redEnd--??1D-Man,p--??1D-GlcNAc,p((--??1D-Gal,p/#zcleavage)--??1L-Fuc,p/#ycleavage)--??1S$MONO,Und,-H,0,redEnd
447.31 0.8
451.23 0.7
464.2 32.9

Annotations:

YY redEnd--??1D-Man,p--??1D-GlcNAc,p((--??1D-Gal,p/#ycleavage)--??1L-Fuc,p/#ycleavage)--??1S$MONO,Und,-H,0,redEnd
464.99 1.9
465.32 1.7
470.92 1.2
475.24 1.9
506.45 0.7
507.21 0.8
515.84 0.8
528.15 0.7

Annotations:

C ?1D-Man,p/#ccleavage--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p)--??1S/#lcleavage$MONO,Und,-H,0,redEnd Z redEnd--??1D-Man,p--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p/#zcleavage)--??1S/#lcleavage$MONO,Und,-H,0,redEnd
536.44 0.9
550.27 0.8
556.21 0.9
567.6 1.1
570.12 2.1
578.43 1.3
584.21 1.1
590.35 24.6

Annotations:

B ?1D-Man,p/#bcleavage--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p)--??1S$MONO,Und,-H,0,redEnd
591.23 8.1
591.52 4.2
592.45 0.9

Annotations:

Z redEnd--??1D-Man,p--??1D-GlcNAc,p((--??1D-Gal,p/#zcleavage)--??1L-Fuc,p)--??1S$MONO,Und,-H,0,redEnd
593.45 1.1
608.32 5.1

Annotations:

C ?1D-Man,p/#ccleavage--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p)--??1S$MONO,Und,-H,0,redEnd Z redEnd--??1D-Man,p--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p/#zcleavage)--??1S$MONO,Und,-H,0,redEnd
609.58 3.9
610.29 124.1

Annotations:

Y redEnd--??1D-Man,p--??1D-GlcNAc,p((--??1D-Gal,p/#ycleavage)--??1L-Fuc,p)--??1S$MONO,Und,-H,0,redEnd
611.26 25.5
612.4 0.8
618.09 1.2
620.32 1.7
622.05 0.9
624.2 0.8
626.29 172.7

Annotations:

Y redEnd--??1D-Man,p--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p/#ycleavage)--??1S$MONO,Und,-H,0,redEnd
627.46 16.2
631.37 0.8
642.32 1.0
650.19 0.6
652.36 3.2
658.64 0.6
661.34 0.9
669.97 5.9
670.35 4.2
673.98 1.3
674.35 5.2
674.71 1.9
676.25 1.0
683.33 1.1
691.25 1.9
699.75 1.2
700.83 1.0
704.19 1.7
710.12 0.8
712.25 0.8
712.71 1.1
713.89 1.1
714.44 1.6
721.5 1.0
724.03 0.7
728.02 1.1
730.33 0.8
732.14 2.4
735.48 1.5
736.13 1.5
736.38 1.5
737.62 1.1
738.42 1.1
772.31 1.1

Annotations:

redEnd--??1D-Man,p--??1D-GlcNAc,p((--??1D-Gal,p)--??1L-Fuc,p)--??1S$MONO,Und,-H,0,redEnd
774.84 0.7

There are 1 similar spectra:

Id Structure Score

6721

0.64

Structure Format

SNFG Oxford Text

Structure details

Reducing Mass: 771.23
(Calculated Monoisotopic)

Reducing End: Reduced

Persubstitution: Underivatised

Biological Context

Taxonomy - Homo Sapiens
Tissue - Brain

HPLC

Column

Method

  • 78 min gradient with approx 3-5 ul/min (static split from 250 ul/min) run rate
  • 10 mM (NH4)HCO3
  • 10 mM (NH4)HCO3 in 80% acetonitrile

Mass Spec

Thermo Fisher LTQ Linear Ion Trap ESI

MIRAGE Structural data

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