A-series gangliosides inhibit TGF-β-induced epithelial-mesenchymal transition via TRI degradation

Jing Zhang, Jin Ma, Hailiang Mei, Cedrick C. Agaser, Birol Cabukusta, Katarina Madunic, Gerard van der Zon, Manfred Wuhrer, Tao Zhang and Peter ten Dijke, Manuscript

Retention Time Recorded Precursor Mass Structure
Not recorded 505.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--3a1D-Gal,p$MONO,Und,-H,0,redEnd
Not recorded 708.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--4a1D-Gal,p--3b1D-GalNAc,p$MONO,Und,-H,0,redEnd
Not recorded 634.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--3a2D-NeuAc,p@270$MONO,Und,-H,0,redEnd
Not recorded 837.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p(--3a2D-NeuAc,p@270)--4b1D-GalNAc,p$MONO,Und,-H,0,redEnd
Not recorded 999.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p(--3a2D-NeuAc,p@270)--4b1D-GalNAc,p--3b1D-Gal,p$MONO,Und,-H,0,redEnd
Not recorded 644.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p(--3a2D-NeuAc,p@270)--4b1D-GalNAc,p--3b1D-Gal,p--3a2D-NeuAc,p@270$MONO,Und,-H,0,redEnd
Not recorded 650.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--3a2D-NeuGc,p@270$MONO,Und,-H,0,redEnd
Not recorded 853.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p(--3a2D-NeuGc,p@270)--4b1D-GalNAc,p$MONO,Und,-H,0,redEnd
Not recorded 652.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p(--3a2D-NeuAc,p@270)--4b1D-GalNAc,p--3b1D-Gal,p--3a2D-NeuGc,p@270$MONO,Und,-H,0,redEnd
Not recorded 925.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--3a2D-NeuAc,p@270--8a2D-NeuAc,p$MONO,Und,-H,0,redEnd
Not recorded 1128.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p(--3a2D-NeuAc,p@270--8a2D-NeuAc,p)--4b1D-GalNAc,p$MONO,Und,-H,0,redEnd
Not recorded 546.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--4b1D-GalNAc,p$MONO,Und,-H,0,redEnd
Not recorded 505.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--4a1D-Gal,p$MONO,Und,-H,0,redEnd
Not recorded 999.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--4b1D-GalNAc,p--3b1D-Gal,p--3a2D-NeuAc,p@270$MONO,Und,-H,0,redEnd
Not recorded 1202.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--4b1D-GalNAc,p--3b1D-Gal,p(--3a2D-NeuAc,p@270)--4b1D-GalNAc,p$MONO,Und,-H,0,redEnd
Not recorded 746.16 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p(--3a2D-NeuAc,p@270)--4b1D-GalNAc,p--3b1D-Gal,p(--3a2D-NeuAc,p@270)--4b1D-GalNAc,p$MONO,Und,-H,0,redEnd
Not recorded 546.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--3b1D-GlcNAc,p$MONO,Und,-H,0,redEnd
Not recorded 708.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--3b1D-GlcNAc,p--4b1D-Gal,p$MONO,Und,-H,0,redEnd
Not recorded 999.0 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--3b1D-GlcNAc,p--4b1D-Gal,p--3a2D-NeuAc,p$MONO,Und,-H,0,redEnd
35.22 505.17 [M -1H]1- redEnd--??1D-Glc,p--4b1D-Gal,p--4b1D-GalNAc,p--3b1D-Gal,p$MONO,Und,-H,0,redEnd

Structure Format

SNFG Oxford Text

Biological Context

N/A

HPLC

Column Hypercarb

Method

  • 73min gradient with 0,6ul/min run rate
  • 10mM ammonium bicarbonate
  • 60% ACN, 10mM ammonium bicarbonate

Mass Spec

Bruker Daltonik amaZon Speed ETD ETD

MIRAGE

See report

UniCarb-DR Creative Commons License

Supported by SIB ExPASy  |  JST / NBDCDICP