Structure

    redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p)--??1S)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd

The O-glycome of human nigrostriatal tissue and its alteration in Parkinsons disease

GlyTouCan Accession Number: Loading...

Peak Intensity
308.01 0.6

Annotations:

C ?1D-GalNAc,p/#ccleavage--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd C b1D-Gal,p/#ccleavage--??2D-NeuAc,p$MONO,Und,-H,0,redEnd
308.57 0.0

Annotations:

C ?1D-GalNAc,p/#ccleavage--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd C b1D-Gal,p/#ccleavage--??2D-NeuAc,p$MONO,Und,-H,0,redEnd
326.04 1.7
326.61 0.0
356.01 1.3
356.58 0.0
368.15 2.3
368.85 0.0
370.08 22.1
370.34 9.4
370.94 0.0
371.46 0.0
422.31 4.1
422.86 0.0
423.4 0.0
444.3 2.5
444.86 0.0
462.42 1.7
463.29 5.2
464.17 380.6

Annotations:

YY redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p/#ycleavage)--??1S)--6a2D-NeuAc,p/#ycleavage$MONO,Und,-H,0,redEnd
465.27 3.2
465.89 0.0
506.02 1.0
506.6 0.0
540.28 3.7
540.85 0.0
541.37 0.0
543.5 1.2
544.05 0.0
553.39 0.8

Annotations:

^{1,3}A_{GalNAc} ?1D-GalNAc,p/#acleavage_1_3--3b1D-Gal,p(--??2D-NeuAc,p)--??1S/#lcleavage$MONO,Und,-H,0,redEnd
553.94 0.0

Annotations:

^{0,2}A_{GalNAc}Z ?1D-GalNAc,p/#acleavage_0_2(--3b1D-Gal,p(--??2D-NeuAc,p/#zcleavage)--??1S/#lcleavage)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd
556.05 0.7

Annotations:

^{2,5}A_{GalNAc}Y ?1D-GalNAc,p/#acleavage_2_5(--3b1D-Gal,p(--??2D-NeuAc,p/#ycleavage)--??1S/#lcleavage)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd
556.61 0.0

Annotations:

^{2,5}A_{GalNAc}Y ?1D-GalNAc,p/#acleavage_2_5(--3b1D-Gal,p(--??2D-NeuAc,p/#ycleavage)--??1S/#lcleavage)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd
568.33 2.6
568.87 0.0
595.65 2.7
596.2 0.0
638.52 1.8
639.06 0.0
657.18 1.0

Annotations:

Z redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p)--??1S/#lcleavage)--6a2D-NeuAc,p/#zcleavage$MONO,Und,-H,0,redEnd Z redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p/#zcleavage)--??1S/#lcleavage)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd
657.77 0.0
661.37 0.9
661.94 0.0
666.66 1.1
667.21 0.0
674.48 0.7
675.04 9.2

Annotations:

Y redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p)--??1S/#lcleavage)--6a2D-NeuAc,p/#ycleavage$MONO,Und,-H,0,redEnd Y redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p/#ycleavage)--??1S/#lcleavage)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd
675.36 31.9

Annotations:

Y redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p)--??1S/#lcleavage)--6a2D-NeuAc,p/#ycleavage$MONO,Und,-H,0,redEnd Y redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p/#ycleavage)--??1S/#lcleavage)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd
675.58 18.8

Annotations:

Y redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p)--??1S/#lcleavage)--6a2D-NeuAc,p/#ycleavage$MONO,Und,-H,0,redEnd Y redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p/#ycleavage)--??1S/#lcleavage)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd
676.3 3.1
676.86 0.0
677.38 1.2
677.94 0.0
689.33 0.5

Annotations:

^{1,5}A_{GalNAc}Z ?1D-GalNAc,p/#acleavage_1_5(--3b1D-Gal,p(--??2D-NeuAc,p/#zcleavage)--??1S)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd
689.87 0.0
690.35 3.1
690.89 0.0
695.57 2.2
696.12 0.0
711.35 12.4
711.61 4.5
712.2 0.0
715.2 3.8
715.75 0.0
716.28 0.0
738.18 0.8
738.77 0.0
750.39 2.4
750.95 0.0
753.65 1.1
754.33 7.2
755.36 165.4

Annotations:

Y redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p)--??1S)--6a2D-NeuAc,p/#ycleavage$MONO,Und,-H,0,redEnd Y redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p/#ycleavage)--??1S)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd
756.2 0.0
756.53 2.0
757.27 3.7
757.85 0.0
758.37 0.0
768.53 1.2
769.1 0.0
770.36 0.5
770.93 0.0
810.41 0.6
810.96 0.0
833.77 2.6
834.34 0.0
836.19 1.6
836.76 0.0
947.69 4.5
948.27 0.0
948.83 0.7
949.39 0.0
965.4 1.3
965.95 0.0

Annotations:

redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p)--??1S/#lcleavage)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd
966.53 6.1

Annotations:

redEnd--??1D-GalNAc,p(--3b1D-Gal,p(--??2D-NeuAc,p)--??1S/#lcleavage)--6a2D-NeuAc,p$MONO,Und,-H,0,redEnd
967.12 0.0
986.24 3.5
986.85 0.0
1002.37 3.1
1002.94 0.0
1003.45 0.0

There are 5 similar spectra:

Id Structure Score

1.00

6596

0.93

0.93

4879

0.69

0.69

Structure Format

SNFG Oxford Text

Structure details

Reducing Mass: 1045.31
(Calculated Monoisotopic)

Reducing End: Reduced

Persubstitution: Underivatised

Biological Context

Taxonomy - Homo Sapiens
Tissue - Brain

HPLC

Column

Method

  • 78 min gradient with approx 3-5 ul/min (static split from 250 ul/min) run rate
  • 10 mM (NH4)HCO3
  • 10 mM (NH4)HCO3 in 80% acetonitrile

Mass Spec

Thermo Fisher LTQ Linear Ion Trap ESI

MIRAGE Structural data

Report errors in this entry

UniCarb-DR Creative Commons License

Supported by SIB ExPASy  |  JST / NBDCDICP